Michelle Elias

About

I am a M.Sc. student in Biophysics at Humboldt University of Berlin with a focus on systems biology, systems medicine and computational pharmacology. My work centers on PBPK modeling, digital twins, and reproducible model pipelines for model informed precision dosing. I am also currently contributing to the DFG Priority Programme SPP 2311 within the research group of Dr. Matthias König.

Currently

Working on reproducible PBPK models for personalized dosing and interindividual variability, and contributing to the DFG Priority Programme SPP 2311 from January 2026.

Publications

Rivaroxaban Pharmacokinetics and Coagulation Effects: Reproducibility of a Physiologically Based Modeling Approach

Myshkina M, Elias M, Casabianca E, König M · Physiome, 2025 · Second Author

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Reproducibility of a Digital Twin of the Angiotensin II Receptor Blocker Losartan

Myshkina M, Elias M, Tensil E, König M · Physiome, 2025 · Second Author

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Reproducibility of a Physiologically Based Pharmacokinetic and Pharmacodynamic (PBPK/PD) Model of Dapagliflozin

Elias M, Myshkina M, Nemitz N, König M · Physiome, 2025 · First Author

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A Digital Twin of Dapagliflozin Pharmacokinetics and Pharmacodynamics in Type 2 Diabetes Mellitus: Modeling Variability in Dosing, Hepatorenal Impairment, and Food Effects

Nemitz N, Elias M and König M · Preprints, 2025 · Co-Author

Submitted Preprint Code

Reproducibility of a Digital Twin of Glimepiride for Personalized and Stratified Diabetes Treatment

Elias M and König M · Physiome, 2025 · First Author

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A digital twin of glimepiride for personalized and stratified diabetes treatment

Elias M and König M · Frontiers in Pharmacology, 2025 · First Author

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